Tindamax (tinidazole) Efficacy and Dosing for Trichomoniasis

Tindamax^® delivers effective treatment in a single dose

Recommended as one of the drugs of choice for treatment of trichomoniasis by the Centers for Disease Control and Prevention (CDC), Tindamax^® has demonstrated cure rates of 92% to 100% in both women and men.

Demonstrated efficacy in clinical trials worldwide

The use of tinidazole (2-g single oral dose) in trichomoniasis has been well documented in 34 published reports from the world literature.

Assessment by culture. In 4 published, blinded, randomized, comparative studies of the 2-g tinidazole single oral dose, efficacy was assessed by culture at time points posttreatment ranging from 1 week to 1 month. Reported cure rates ranged from 92% (37/40) to 100% (65/65) (n=172 total subjects).
Assessment by wet mount. In another group of 4 published, blinded, randomized comparative studies, efficacy was assessed by wet mount between 7-14 days posttreatment. Reported cure rates ranged from 80% (8/10) to 100% (16/16) (n=116 total subjects).

Trichomoniasis cure rates with Tindamax^®

Chart summarizing cure rates following treatment with Tindamax<sup class='reg'>®</sup>. 96% cure rate was achieved with 2-gram stat oral dosing in female patients. 94% cure rate was achieved with 2-gram stat oral dosing in male patients.

* Average of 4 studies with cure rate range of 92%-100% at 1 week to 1 month postdosing.^1-4

** Average of 4 studies with cure rate range of 83%-100%.^5-8

Dosing recommendations for trichomoniasis
Indication	Adults	Children
Trichomoniasis	2 g single dose	n/a
§ CI: confidence interval p-values for both Tindamax^® regimens vs. placebo for therapeutic, clinical and Nugent score cure rates for both 2 and 5 days <0.001

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Gabriel G, Robertson E, Thin RN. J Int Med Res. 1982;10(2):129-30. J Int Med Res. 1982;10(2):129-30.
Hillström L, Pettersson L, Pálsson E, Sandström SO. Comparison of ornidazole and tinidazole in single-dose treatment of trichomoniasis in women. Br J Vener Dis. 1977 Jun;53(3):193-4.
Aimakhu V. Vaginal trichomoniasis: one stat dose of tinidazole compared with a seven day course of metronidazole. W Afr Med J. 1975 Apr;97-100.
Beric B, Pribicevic V, Djordjevic M, Pavlovic N. Clinical studies on the therapeutic effect of tinidazole ("Fasigyn") during treatment of urogenital trichomonas infections in women and men (with comparative laboratory studies on the effect of metronidazole and tinidazole) Zentralbl Gynakol. 1978;100(24):1594-9.
Massa M, Arias B, Subiabre V, Rojo M. Ensayo terapeutico de la infeccion por Trichomonas vaginalis en el hombre mediate una dosis unica de tinidazol. Bol Chile Parasitol. 1976 Jan-Jun;31(1-2):46-7.
Wallin J, Forsgren A. Tinidazole--a new preparation for T. vaginalis infections. II. Clinical evaluation of treatment with a single oral dose. Br J Vener Dis. 1974 Apr;50(2):148-50.
Fantini E, Leguen J, Kellemberger J, Rubi R. Treatment of trichomoniasis in males with a single dose of a new imidazole derivative. Sem Med. 1974 Jul;46-50.