If you're diagnosed with trichomoniasis, your doctor may prescribe Tindamax®, an oral antibiotic that is effective for treating trichomoniasis.
Treating trichomoniasis with Tindamax®
- Tindamax is recommended as one of the drugs of choice for the treatment of trichomoniasis by the Centers for Disease Control and Prevention (CDC).
- In over 30 clinical studies of trichomoniasis, Tindamax has demonstrated cure rates of 92 to 100 percent in both women and men.
- Tindamax effectively treats trichomoniasis in one dose, while sparing protective vaginal lactobacilli.
Trichomoniasis cure rates with Tindamax®
* Average of 4 studies with cure rate range of 92%-100% at 1 week to 1 month postdosing.1-4
** Average of 4 studies with cure rate range of 83%-100%.5-8
Easy, effective treatment in just one dose
Tindamax® is a widely prescribed treatment for TV that requires just one dose to deliver highly effective results.
- A single 2-gram dose has demonstrated cure rates of 92% to 100% in both women and men.
- A low risk of side effects, including GI symptoms such as nausea, vomiting, and diarrhea, make Tindamax® easy to tolerate.4
The only therapy approved to treat both BV and TV infections
Bacterial vaginosis and trichomoniasis frequently occur together and may have similar signs and symptoms, including an abnormal vaginal discharge and unpleasant "fishy" odor. Specific tests and laboratory analysis are often used to precisely diagnose BV and TV.5
If your test results indicate that you have a mixed infection, one therapy can treat them both with proven, effective results: Tindamax®.
Important Safety Information
WARNING: POTENTIAL RISK FOR CARCINOGENICITY
Carcinogenicity has been seen in mice and rats treated chronically with metronidazole, another nitroimidazole agent. Although such data have not been reported for tinidazole, the two drugs are structurally related and have similar biologic effects. Its use should be reserved for the conditions described in INDICATIONS AND USAGE.
Tindamax® is a prescription antibiotic used to treat certain infections caused by bacteria and parasites. It is approved for treating trichomoniasis, also known as "trich," and bacterial vaginosis, or "BV" (in non-pregnant, adult women). It is also approved for treating giardiasis, also known as "giardia," amebiasis, and amebic liver abscess in patients age 3 and older.
Important Safety Information
Tindamax® is not for everyone. You should not take Tindamax® if you are in the first trimester of pregnancy. If you are nursing, Tindamax® can pass through your breast milk, so you should not take it unless you stop breastfeeding during your prescription and for 3 days after your last dose.
Tindamax® can lead to a temporary reduction in your white blood cells, so if you have been diagnosed with a blood disorder, talk to your doctor before starting a prescription.
Do not take Tindamax® if you have a history of sensitivity to tinidazole or related drugs in the nitroimidazole family. Reactions can range from mild itching, hives, or fever to Stevens-Johnson syndrome, which is a rare, life-threatening skin condition.
Certain drugs may interact with Tindamax®, so always tell your doctor about the medications you're taking before you start a prescription.
Take each dose of Tindamax® with food to lessen the risk of stomach upset and other GI side effects. Avoid any alcoholic beverages while taking Tindamax® and for 3 days afterward.
If you are undergoing hemodialysis while taking Tindamax® on the same day, consult your doctor for the appropriate dose of Tindamax®. An additional half-dose of Tindamax® at the end of dialysis may be recommended.
Antibacterial drugs, including Tindamax®, do not treat viral infections such as the common cold. When taking Tindamax® to treat a bacterial infection, it is very common to feel better early in your prescription; however, you should keep taking the medication as directed and for as long as directed by your doctor. Skipping doses or not taking all of your medication can make Tindamax® less effective. It can also allow the bacteria to build up resistance to the drug, so that it won't be treatable with Tindamax® or similar drugs in the future.
The most common side effects of Tindamax® are a metallic or bitter taste, nausea, weakness, fatigue, discomfort, indigestion, cramps, vomiting, loss of appetite, headache, dizziness, and constipation.
Some patients taking Tindamax® may also develop a yeast infection, which can require treatment with an anti-fungal drug. Talk to your doctor if you notice any unusual symptoms.
Certain patients taking Tindamax® have experienced seizures or nerve problems, with symptoms such as numbness or tingling of the hands or feet. Other side effects included vertigo, unsteady movements, insomnia, or drowsiness. Stop taking Tindamax® if you develop any abnormal symptoms.
Tinidazole, the key ingredient in Tindamax®, is related to a drug called metronidazole, which has been linked to cancer in lab rats and mice that received the drug over long periods of time. Although these effects have not been reported for tinidazole, the two drugs are chemically related and have similar effects on the body. Therefore, Tindamax® should only be used to treat infections it has been approved to treat.
To report negative side effects, contact Mission Pharmacal Company at 1-800-298-1087 or the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
- O-Prasertsawat P, Jetsawangsri T. Split-dose metronidazole or single-dose tinidazole for the treatment of vaginal trichomoniasis. Sex Transm Dis. 1992 Sep-Oct;19(5):295-7.
- Gabriel G, Robertson E, Thin RN. J Int Med Res. 1982;10(2):129-30. J Int Med Res. 1982;10(2):129-30.
- Hillström L, Pettersson L, Pálsson E, Sandström SO. Comparison of ornidazole and tinidazole in single-dose treatment of trichomoniasis in women. Br J Vener Dis. 1977 Jun;53(3):193-4.
- Aimakhu V. Vaginal trichomoniasis: one stat dose of tinidazole compared with a seven day course of metronidazole. W Afr Med J. 1975 Apr;97-100.
- Beric B, Pribicevic V, Djordjevic M, Pavlovic N. Clinical studies on the therapeutic effect of tinidazole ("Fasigyn") during treatment of urogenital trichomonas infections in women and men (with comparative laboratory studies on the effect of metronidazole and tinidazole) Zentralbl Gynakol. 1978;100(24):1594-9.
- Massa M, Arias B, Subiabre V, Rojo M. Ensayo terapeutico de la infeccion por Trichomonas vaginalis en el hombre mediate una dosis unica de tinidazol. Bol Chile Parasitol. 1976 Jan-Jun;31(1-2):46-7.
- Wallin J, Forsgren A. Tinidazole--a new preparation for T. vaginalis infections. II. Clinical evaluation of treatment with a single oral dose. Br J Vener Dis. 1974 Apr;50(2):148-50.
- Fantini E, Leguen J, Kellemberger J, Rubi R. Treatment of trichomoniasis in males with a single dose of a new imidazole derivative. Sem Med. 1974 Jul;46-50.
Websites
For Health Professionals
Only Tindamax® is approved to treat both bacterial vaginosis and trichomoniasis (TV).
Clinical Insight
Oral vs vaginal cream therapy: Patient preference for oral dosing is demonstrated to be 84%. More»
Beyond BV
Tindamax® may be prescribed for other infections including:
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